Internet Virtual Exhibition for Life Science Industry

Tokai Hit Co., Ltd.

Tokai Hit is a global company that supports medical care and research around the world from the foot of Mt. Fuji.

Business Category : Process Equipment、Regenerative medicine treatment、Materials for research and development

Main Service Region : Japan、Canada、United States、China、Korea, Republic of、Taiwan、Indonesia、Malaysia、Philippines、Singapore、Thailand、Viet Nam、Europe(excluding UK)、United Kingdom、India、Other Countries

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Products & Services

2021/11/08

Program fluidic control system PMD-D21B

API、Analysis、Clinical、Modality

Pump unit can be installed in a CO2  incubator

【Components】

・Controller, Pump, Tube set

Inside the incubator

 

【Features】

Pump unit can be installed in a CO2 incubator

Adopts moisture-proof design and shield technology.
It is possible to install a perfusion system including a pump in a CO2 incubator.

 

Programmatic operation of continuous perfusion and media exchange is possible

Any protocol can be created by combining continuous perfusion and media exchange.
(Maximum 8 steps, 14 repeats)

 

Reliable perfusion with leveling function

Reproducible media exchange is possible with our unique leveling technology.
Maintains a stable amount of media during long-term continuous perfusion and high-flow media exchange.

 

 

【Basic specifications】

Continuous perfusion Flow range:0.04 ~ 0.1 mL/min
Time settings:Max. 14 days
Media exchange Flow range:0.6 ~ 5.0 mL/min
Repeat count:Max. 10 times
Program Number of steps:Max. 8
Program repeat:Max. 14 times
TTL mode Input:Over 5V 20msec
Output:5V 20 ~ 1000msec variable
*Any program operation is possible with TTL input.

 

【Application】

・Media Exchange
・Perfusion Culture
・Tissue Engineering
・3D Culture
・Organoid
・Biomimetics

 

Sealed lids and Dish attachment for 35mm dish

Sealed lids with pipes for perfusion and drug delivery
Dish attachment for 35mm dish x 2 pcs

Compatible with:Corning / Matsunami / MatTek / Eppendorf / Nunc / Greiner

 

【Image】

 

More Details

2021/11/08

Pulsating Constant Pressure Pump BPU series

API、Analysis、Clinical、Modality

【Features】

Non-contact pressure measurement

It measures the flow path pressure during perfusion aseptically.
By feeding back to the pump, constant pressure liquid feeding is also possible.

 

Pump unit can be installed in a COincubator

Adopts moisture-proof design and shield technology
It is possible to install a perfusion system including a pump in a CO2 incubator.
It controls the two channels independently.

 

Touch panel controller

You can intuitively switch between constant pressure/pulsation constant pressure/constant flow rate perfusion mode.
The data logging function is available as standard.

 

【Components】

Controller

It controls the pump and set the parameter.

A touch panel is used to operate the pump at a pulsating constant pressure,

constant pressure, and constant flow rate.

Pump

The pumps are in a container with a moisture-proof design and shield technology.

It controls each of the two-channel lines and the two pumps independently.

There is one pump that can be used for general purposes such as drainage in the container.

Buffer bottle

Using a unique mechanism that measures the flow path pressure via a buffer bottle.

Aseptic and reusable sensing of channel pressure is possible.

 

【Specifications】

Model BPU
Components

Controller

Buffer bottle

Pump

Size

Pump unit:W175 x H164 x D214 (mm)
Controller:W150 x H126 x D199 (mm)
Cable length:2.0 (m)

Pressure range

●Pulsating constant pressure mode

 Pressure setting range: 0 to 200 mmHg

 Time setting: 1 sec

●Constant pressure mode

 Pressure setting range: 0 to 200 mmHg

 Setting STEP: 1 mmHg

 

●Constant flow mode

 Flow rate setting range: 0.3-42.0 ml / min

 Setting STEP: 0.1 ml / min

More Details

2021/10/27

Incubation system for microscopes Stage Top Incubator®

API、Development、Analysis

Offers precision temperature, humidity and CO2 control for cell culture on a microscope.
Enables to conduct short and long term (more than 2 weeks) Time-Lapse Imaging.
 

By applying Real-time Sample Feedback Regulation, it can maintain an optimal cell culture environment
which is as same as the conventional CO2 incubator.
 

With our variety of options, we can offer solutions for abundant applications, and leading the experiment to success.

 

【Features】

Accurate and uniform temperature control

TOKAI HIT Heating Quality

Tokai Hit's original Top Heater is proven to distribute heat uniformly within the Chamber regardless of the type of vessels.

No interference by objective

With unique Top Heater Heating Time regulation, the bottom of Chamber is access-free for variety of objectives. (No metal plate at the bottom.)

Real-time Sample Feedback Regulation

Sterilized temperature sensor and magnetic lids make it easy to measure the temp. of culture media upon research needs.
The controller regulates the heater based on the sensor signal to keep sample at the target temp. accurately.

 

Apply Internal Humidifier to keep high humidity condition during the imaging

Keeps high humidity inside the chamber by heating the distilled water in the Bath Unit.
Internal Humidifier minimizes the change in concentration of media by keeping the humidity inside the chamber.

 

Stable CO2 environment

The controller mixes 100%CO2 gas and the surrounding air automatically. Stable gas concentration inside the Chamber is obtained by keep sending the mixed gas to the Chamber.
(※In case of controller with a built-in digital gas mixer)

 

【Line-up】

Applicable stage

Gas type Model
manual/motorized stage
with 160 x 110mm opening
With built-in digital gas mixer * For 100%CO2 gas cylinder use STXG-WSKMX-SET
With built-in analog flow meter * For premixed gas cylinder use STXF-WSKMX-SET
Olympus manual/
motorized stage
With built-in digital gas mixer * For 100%CO2 gas cylinder use STXG-IX3WX-SET
With built-in analog flow meter * For premixed gas cylinder use STXF-IX3WX-SET
Nikon Ti/Ti2
exclusive piezo stage
With built-in digital gas mixer * For 100%CO2 gas cylinder use STXG-TIZWX-SET
With built-in analog flow meter * For premixed gas cylinder use STXF-TIZWX-SET
Nikon Ti/Ti2
exclusive piezo stage
With built-in digital gas mixer * For 100%CO2 gas cylinder use STXG-TIZBX-SET
With built-in analog flow meter * For premixed gas cylinder use STXF-TIZBX-SET
Leica manual/motorized stage
(with Laser Safety Hood)
With built-in digital gas mixer * For 100%CO2 gas cylinder use STXG-DMIWX-SET
With built-in analog flow meter * For premixed gas cylinder use STXF-DMIWX-SET
Leica SP8/SP5
Super Z Galvo stage
With built-in digital gas mixer * For 100%CO2 gas cylinder use STXG-GSI2X-SET
With built-in analog flow meter * For premixed gas cylinder use STXF-GSI2X-SET
Zeiss piezo stage
WSB-500
With built-in digital gas mixer * For 100%CO2 gas cylinder use STXG-WSBX-SET
With built-in analog flow meter * For premixed gas cylinder use STXF-WSBX-SET
Manual/motorized/
mechanical stage
With built-in digital gas mixer * For 100%CO2 gas cylinder use STXG-WELSX-SET
With built-in analog flow meter * For premixed gas cylinder use STXF-WELSX-SET

We offer various lineups depending on the microscope, stage, and vessels etc.

Please feel free to contact us anytime.

More Details

2021/10/27

Clean Enclosure for microscopes PureBox SHIRAITO®

Analysis、API、Development、Testing、Modality

Suitable for sterility operation during imaging

Enable to achieve clean bench cleanness/sterility environment on the microscope.

 

Recommend when:

  • CARE the cleanness of microscope environment during operation.
  • Image cells after clean bench manipulation (e.g. induce cell differentiation by media exchange, etc)
  • For temperature sensitive sample imaging.
  • Wish to remove vessels lid for conducting drug delivery/media exchange during time-lapse imaging.
  • Transplant the imaged cells/sample.
  • For the sample which cannot add antibiotics into the media. The real live cell imaging without antibiotics possible.

Target applications:

  • iPS cells/researches
  • Organoid study
  • Pharmceutical field
  • Food research
  • Embryo study, etc.

 

Same sterility level as the clean bench

Achieve same sterility as level 100 (ISO class 5) on the microscope and maintain cleanliness levels during imaging.

 

Compatible with complex microscope applications

Installation of microscope add-on system such as confocal equipment is possible
that clean bench cannot to accommodate.

 

Red LED light and contactless LED switch

Red LED (longer wavelength) is integrated.
White and red lights can be switched with a single switch.
With the contactless switch, you can turn on/off the LED light without touching the system during experiments.

 

 

【Line-up】

Applicable microscope Model Image
Olympus IX83 IX83PBS
Nikon Ti2 TI2PBS
Leica DMi8 DMi8PBS

Depending on the accessories (camera, stage, etc.), the model may be a customized model. Please contact us for details.

More Details

2021/10/27

Enclosure for microscopes ThermoBox

Manufacturing、API、Analysis、Development、Modality、Clinical

Suitable for microscope environemt control.

It allows to prevent focus drift caused by environmental disturbances and keep the preheat-media (bottle), objectives, etc under same temperature.

 

No duct required

Saves your working and setting space with built-in fan heaters. No air-duct is required for heating.

 

Anti-vibration heater

With anti-vibration design, the system can be used under confocal without image drift.

 

Simple Dark Room use

The Dark type can prevent sample from light exposure and work as simple dark room.

 

 

【Line-up】

Microscope/stage Color type Heater Model
Olympus IX83 Black With heater IX83TB-BK-LED
Without heater IX83TB-BK-NH-LED
Front clear With heater IX83TB
Without heater IX83TB-NH
Nikon TI2
Motorized stage
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<TI2-S-SS-E>
Black With heater TI2TB-E-BK
Without heater TI2TB-E-BK-NH
Front clear With heater TI2TB-E
Without heater TI2TB-E-NH
Nikon TI2
Manual stage
<TC-S-SR/SRF>
Black With heater TI2TB-M-BK
Without heater TI2TB-M-BK-NH
Front clear With heater TI2TB-M
Without heater TI2TB-M-NH

Leica DMi8
Motorized stage

Black With heater DMi8TB-BK
Without heater

DMi8TB-BK-NH

Leica DMi8
3 plate stage(Motorized stage)

Black With heater DMi8TB-3E-BK
Without heater

DMi8TB-3E-BK-NH

Zeiss Axio Observer
Motorized stage (130×100 STEP)
Manual stage

Black With heater AXIOTB-BK
Without heater AXIOTB-BK-NH

Depending on the accessories (camera, stage, etc.), the model may be a customized model. Please contact us for details.

More Details

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